Twilio gives you the phone network and the building blocks. Retell gives you the agent, and it runs on Twilio numbers too.
Twilio is the telephony layer much of the industry runs on, with phone numbers in 100+ countries and more than 400,000 customer accounts. For voice AI it offers building blocks: Conversation Relay handles speech-to-text, text-to-speech and the call session over a WebSocket, and Media Streams sends raw call audio to your own systems.
Twilio does not host the agent. With Conversation Relay, your team brings the LLM, runs the WebSocket server that holds the conversation logic, and builds handoffs to people in your own call-control code.
Retell is the agent layer. It handles transcription, turn-taking, the LLM, voices and call control in one platform, and it works with Twilio: use Retell numbers that run on Twilio, or connect your existing Twilio numbers over elastic SIP trunking.
Keep your Twilio numbers. Skip building the agent.
What your team builds on each
Compare what you would build on Twilio's voice AI building blocks with what comes ready on Retell, from LLM hosting to HIPAA coverage.
Add the agent without changing your carrier
Twilio is the right foundation for teams building communications into their own product.
Retell is the right choice when the goal is calls handled well, not an agent stack to maintain.